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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EDEM1 antibody - N-terminal region   

EDEM1 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - EDEM1 antibody - N-terminal region AI12744

    WB Suggested Anti-EDEM1 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: 721_B cell lysate
    EDEM1 is supported by BioGPS gene expression data to be expressed in 721_B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92611
Other Accession NM_014674, NP_055489
Reactivity Human, Mouse, Rat, Rabbit, Pig, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 74kDa
Additional Information
Gene ID 9695
Alias Symbol EDEM, KIAA0212
Other Names ER degradation-enhancing alpha-mannosidase-like protein 1, EDEM1, EDEM, KIAA0212
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-EDEM1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsEDEM1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EDEM1
Synonyms EDEM, KIAA0212
Function Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein
Research Areas
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$ 293.00
Cat# AI12744
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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