IMPG2 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9BZV3 |
Other Accession | NM_016247, NP_057331 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Chicken, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 138kDa |
Gene ID | 50939 |
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Alias Symbol | IPM 200, IPM200, SPACRCAN, RP56 |
Other Names | Interphotoreceptor matrix proteoglycan 2, Interphotoreceptor matrix proteoglycan of 200 kDa, IPM 200, Sialoprotein associated with cones and rods proteoglycan, Spacrcan, IMPG2, IPM200 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-IMPG2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | IMPG2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | IMPG2 |
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Synonyms | IPM200 |
Function | Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix; may participate in the maturation and maintenance of the light-sensitive photoreceptor outer segment. Binds heparin. |
Cellular Location | Photoreceptor outer segment membrane; Single-pass type I membrane protein. Photoreceptor inner segment membrane {ECO:0000250|UniProtKB:Q80XH2}; Single-pass type I membrane protein. Secreted, extracellular space, extracellular matrix, interphotoreceptor matrix |
Tissue Location | Expressed in the retina (at protein level) (PubMed:10702256, PubMed:29777959). Expressed by photoreceptors of the interphotoreceptor matrix (IPM) surrounding both rods and cones (at protein level) (PubMed:10542133, PubMed:29777959). IPM occupies the subretinal space between the apices of the retinal pigment epithelium and the neural retina (PubMed:10542133). Expressed in the pineal gland (at protein level) (PubMed:10702256). |
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Provided below are standard protocols that you may find useful for product applications.
References
Acharya,S.,(2000)J.Biol.Chem.275(10),6945-6955ReconstitutionandStorage:Forshorttermuse,storeat2-8Cupto1week.Forlongtermstorage,storeat-20Cinsmallaliquotstopreventfreeze-thawcycles.
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