|Other Accession||NM_016256, NP_057340|
|Reactivity||Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||APAA, UCE|
|Other Names||N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, 22.214.171.124, Mannose 6-phosphate-uncovering enzyme, Phosphodiester alpha-GlcNAcase, NAGPA|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-NAGPA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NAGPA Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides by removing GlcNAc residues from GlcNAc-alpha-P- mannose moieties, which are formed in the first step. Also hydrolyzes UDP-GlcNAc, a sugar donor for Golgi N- acetylglucosaminyltransferases.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network. Note=Cis/medial Golgi|
|Tissue Location||Isoform 2 may be brain-specific.|
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