TM7S3 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9NS93 |
Other Accession | NP_057635 |
Reactivity | Human |
Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 62kDa |
Gene ID | 51768 |
---|---|
Alias Symbol | TM7SF3, |
Other Names | Transmembrane 7 superfamily member 3, Seven span transmembrane protein, TM7SF3 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-TM7S3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | TM7S3 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TM7SF3 |
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Function | Involved in the inhibition of cytokine-induced death of pancreatic beta cells. Involved in the promotion of insulin secretion from pancreatic beta cells (PubMed:21853325). Is a downstream transcriptional target of p53/TP53, and acts as a pro-survival homeostatic factor that attenuates the development of cellular stress. Maintains protein homeostasis and promotes cell survival through attenuation of endoplasmic reticulum (ER) stress and the subsequent induction of unfolded protein response (UPR) (PubMed:27740623). |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Widely expressed. Highly expressed in kidney and pancreas. |
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