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Mafk antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Mafk antibody - N-terminal region AI12810

    WB Suggested Anti-Mafk Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Liver
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q61827
Other Accession NM_010757, NP_034887
Reactivity Human, Mouse, Rat, Zebrafish, Pig, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 17kDa
Additional Information
Gene ID 17135
Alias Symbol AW061068, NF-E2, Nfe2u
Other Names Transcription factor MafK, Erythroid transcription factor NF-E2 p18 subunit, Mafk, Nfe2u
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Mafk antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsMafk antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mafk
Synonyms Nfe2u
Function Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves (By similarity). However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites (PubMed:9240432). Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor (By similarity).
Cellular Location Nucleus.
Tissue Location Highly expressed in heart, skeletal muscle and placenta. Also expressed in erythroid cells
Research Areas
Citations (0)
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$ 389.00
Cat# AI12810
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