|Other Accession||NM_172527, NP_766115|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Zebrafish, Chicken, Guinea Pig, Dog|
|Alias Symbol||6530403O17, A730068G11Rik, MTH2|
|Other Names||Probable 8-oxo-dGTP diphosphatase NUDT15, 8-oxo-dGTPase NUDT15, 220.127.116.11, 7, 8-dihydro-8-oxoguanine-triphosphatase NUDT15, MutT homolog 2, mMTH2, Nucleoside diphosphate-linked moiety X motif 15, Nudix motif 15, Nudt15, Mth2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Nudt15 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Nudt15 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.