AS3MT antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9HBK9 |
Other Accession | NM_020682, NP_065733 |
Reactivity | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Chicken, Goat, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 42kDa |
Gene ID | 57412 |
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Alias Symbol | CYT19, RP11-753C18.6 |
Other Names | Arsenite methyltransferase, 2.1.1.137, Methylarsonite methyltransferase, S-adenosyl-L-methionine:arsenic(III) methyltransferase, AS3MT, CYT19 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-AS3MT antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | AS3MT antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AS3MT |
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Synonyms | CYT19 |
Function | Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals (PubMed:16407288, PubMed:25997655). It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2 (PubMed:16407288, PubMed:25997655). Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (PubMed:16407288, PubMed:25997655). |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q8VHT6} |
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