Trmt5 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9D0C4 |
Other Accession | NM_029580, NP_083856 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Chicken, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 57kDa |
Gene ID | 76357 |
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Alias Symbol | 2610027O18Rik, KIAA1393, mKIAA1393 |
Other Names | tRNA (guanine(37)-N1)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, 2.1.1.228 {ECO:0000255|HAMAP-Rule:MF_03152}, M1G-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, tRNA [GM37] methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152}, tRNA methyltransferase 5 homolog {ECO:0000255|HAMAP-Rule:MF_03152}, Trmt5, Kiaa1393, Trm5 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Trmt5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Trmt5 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Trmt5 |
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Synonyms | Kiaa1393, Trm5 |
Function | Involved in mitochondrial tRNA methylation (By similarity). Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding. |
Cellular Location | Mitochondrion matrix {ECO:0000255|HAMAP- Rule:MF_03152}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03152}. Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03152}. Note=Predominantly in the mitochondria and in the nucleus. {ECO:0000255|HAMAP-Rule:MF_03152} |
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