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B3gnt7 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8K0J2 |
| Other Accession | NM_145222, NP_660257 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Guinea Pig, Dog |
| Predicted | Rabbit, Pig, Horse, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Gene ID | 227327 |
|---|---|
| Alias Symbol | C330001H22Rik, beta-3GnT7 |
| Other Names | UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 7, BGnT-7, Beta-1, 3-Gn-T7, Beta-1, 3-N-acetylglucosaminyltransferase 7, Beta3Gn-T7, 2.4.1.-, B3gnt7 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-B3gnt7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | B3gnt7 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | B3gnt7 |
|---|---|
| Function | N-acetyl glucosamine (GlcNAc) transferase that catalyzes the transfer of GlcNAc via a beta1->3 linkage from UDP-GlcNAc to the non- reducing terminal galactose (Gal) in the linearly growing chain of N- and O-linked keratan sulfate proteoglycans. Cooperates with B4GALT4 galactosyltransferase and CHST6 and CHST1 sulfotransferases to construct and elongate mono- and disulfated disaccharide units [->3Galbeta1->4(6-sulfoGlcNAcbeta)1->] and [->3(6-sulfoGalbeta)1->4(6- sulfoGlcNAcbeta)1->] within keratan sulfate polymer (By similarity). Involved in biosynthesis of N-linked keratan sulfate proteoglycans in cornea, with an impact on proteoglycan fibril organization and corneal transparency (PubMed:29625490). May play a role in the maintenance of tissue architecture by suppressing cellular motility and invasion (PubMed:12061784). |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Strongly expressed in placenta and colon. Moderately expressed in lung, stomach, small intestine and kidney. Very weakly expressed in cerebrum, cerebellum, heart and testis |
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Kataoka K.,et al.Biochem. Biophys. Res. Commun. 294:843-848(2002).
Carninci P.,et al.Science 309:1559-1563(2005).
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$ 389.00
Cat# AI12976
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