C14orf172 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q96FX7 |
Other Accession | NM_152307, NP_689520 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 31kDa |
Gene ID | 115708 |
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Alias Symbol | FLJ40452, GCD14, Gcd14p, TRM61, hTRM61, C14orf172 |
Other Names | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A, 2.1.1.220, tRNA(m1A58)-methyltransferase subunit TRMT61A, tRNA(m1A58)MTase subunit TRMT61A, TRMT61A, C14orf172, TRM61 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-C14orf172 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | C14orf172 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TRMT61A |
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Synonyms | C14orf172, TRM61 |
Function | Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508). Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P46959}. |
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Provided below are standard protocols that you may find useful for product applications.
References
Heilig R.,et al.Nature 421:601-607(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ozanick S.,et al.RNA 11:1281-1290(2005).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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