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C14orf172 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - C14orf172 antibody - N-terminal region AI12977

    WB Suggested Anti-C14orf172 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: SH-SYSY cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q96FX7
Other Accession NM_152307, NP_689520
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 31kDa
Additional Information
Gene ID 115708
Alias Symbol FLJ40452, GCD14, Gcd14p, TRM61, hTRM61, C14orf172
Other Names tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A, 2.1.1.220, tRNA(m1A58)-methyltransferase subunit TRMT61A, tRNA(m1A58)MTase subunit TRMT61A, TRMT61A, C14orf172, TRM61
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-C14orf172 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsC14orf172 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRMT61A
Synonyms C14orf172, TRM61
Function Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508). Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297).
Cellular Location Nucleus {ECO:0000250|UniProtKB:P46959}.
Citations (0)
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References

Heilig R.,et al.Nature 421:601-607(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ozanick S.,et al.RNA 11:1281-1290(2005).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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$ 389.00
Cat# AI12977
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