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B3GALNT2 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - B3GALNT2 antibody - middle region AI12979

    WB Suggested Anti-B3GALNT2 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: Human brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8NCR0
Other Accession NM_152490, NP_689703
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 57kDa
Additional Information
Gene ID 148789
Alias Symbol B3GalNAc-T2, MGC39558
Other Names UDP-GalNAc:beta-1, 3-N-acetylgalactosaminyltransferase 2, Beta-1, 3-GalNAc-T2, 2.4.1.-, Beta-1, 3-N-acetylgalactosaminyltransferase II, B3GALNT2
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-B3GALNT2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsB3GALNT2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1- 3GlcNAc, on N- and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan (DAG1) glycosylation: acts coordinately with GTDC2/POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine- beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein. Endoplasmic reticulum
Tissue Location Expressed in all tissues examined, but at highest levels in testis, adipose tissue, skeletal muscle and ovary.
Citations (0)

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Gregory S.G.,et al.Nature 441:315-321(2006).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Hiruma T.,et al.J. Biol. Chem. 279:14087-14095(2004).
Stevens E.,et al.Am. J. Hum. Genet. 92:354-365(2013).
Yoshida-Moriguchi T.,et al.Science 341:896-899(2013).

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$ 293.00
Cat# AI12979
(40 western blots)
Availability: 2-3 days
Bulk Size
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