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Tmem165 Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P52875 |
| Other Accession | NM_011626, NP_035756 |
| Reactivity | Human, Mouse, Rat, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35kDa |
| Gene ID | 21982 |
|---|---|
| Alias Symbol | AV026557, Tpardl, Tparl, pFT27 |
| Other Names | Transmembrane protein 165, TPA-regulated locus protein, Transmembrane protein PFT27, Transmembrane protein TPARL, Tmem165, Tparl |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Tmem165 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Tmem165 Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Tmem165 {ECO:0000303|PubMed:30622138, ECO:0000312|MGI:MGI:894407} |
|---|---|
| Function | Putative divalent cation:proton antiporter that exchanges calcium or manganese ions for protons across the Golgi membrane. Mediates the reversible transport of calcium or manganese to the Golgi lumen driven by the proton gradient and possibly the membrane potential generated by V-ATPase. Provides calcium or manganese cofactors to resident Golgi enzymes and contributes to the maintenance of an acidic luminal Golgi pH required for proper functioning of the secretory pathway (By similarity). Promotes Ca(2+) storage within the Golgi lumen of the mammary epithelial cells to be then secreted into milk (PubMed:30622138). The transport mechanism and stoichiometry remains to be elucidated (By similarity). |
| Cellular Location | Golgi apparatus membrane; Multi-pass membrane protein |
| Tissue Location | Expressed in mammary epithelial cells (at protein level). |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Akagi J.,et al.Biochem. Biophys. Res. Commun. 157:548-557(1988).
Wilsbacher L.D.,et al.Genome Res. 10:1928-1940(2000).
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$ 389.00
Cat# AI13014
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