|Application ||WB, IHC|
|Other Accession||NM_018509, NP_060979|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rabbit, Pig, Guinea Pig, Dog|
|Alias Symbol||FLJ21675, PRO1855|
|Other Names||Leucine-rich repeat-containing protein 59, Protein p34, Lrrc59, Rbp34|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LRRC59 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LRRC59 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for nuclear import of FGF1, but not that of FGF2. Might regulate nuclear import of exogenous FGF1 by facilitating interaction with the nuclear import machinery and by transporting cytosolic FGF1 to, and possibly through, the nuclear pores (By similarity).|
|Cellular Location||Microsome membrane; Single- pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein. Nucleus envelope. Note=Localization in the nuclear envelope depends upon the nuclear import machinery, including KPNB1.|
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Provided below are standard protocols that you may find useful for product applications.
Ohsumi T.,et al.Biochem. J. 294:465-472(1993).
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