|Other Accession||NM_019078, NP_061951|
|Alias Symbol||UDPGT, UGT1E, UDPGT 1-5|
|Other Names||UDP-glucuronosyltransferase 1-5, UDPGT 1-5, UGT1*5, UGT1-05, UGT1.5, 188.8.131.52, UDP-glucuronosyltransferase 1-E, UGT-1E, UGT1E, UDP-glucuronosyltransferase 1A5, UGT1A5, GNT1, UGT1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-UGT1A5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||UGT1A5 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity).|
|Cellular Location||Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Isoform 1 and isoform 2 are expressed in colon and small intestine. Neither isoform is expressed in liver, kidney or esophagus.|
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Provided below are standard protocols that you may find useful for product applications.
Ritter J.K.,et al.J. Biol. Chem. 267:3257-3261(1992).
Gong Q.H.,et al.Pharmacogenetics 11:357-368(2001).
Hillier L.W.,et al.Nature 434:724-731(2005).
Guillemette C.,et al.Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
Girard H.,et al.Pharmacogenet. Genomics 17:1077-1089(2007).
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