Entpd7 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q3TCT4 |
Other Accession | NM_053103, NP_444333 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 69kDa |
Gene ID | 93685 |
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Alias Symbol | 1810012B13Rik, 1810020C02Rik, 2810003F23Rik, LALP1, Lysal2 |
Other Names | Ectonucleoside triphosphate diphosphohydrolase 7, NTPDase 7, 3.6.1.-, Lysosomal apyrase-like protein 1, Entpd7, Kiaa4066, Lalp1 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Entpd7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Entpd7 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Entpd7 |
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Synonyms | Kiaa4066, Lalp1 {ECO:0000303|PubMed:1127 |
Function | Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Preferentially hydrolyzes nucleoside 5'-triphosphates, with substrate preference for UTP > GTP > CTP. Hydrolyzes nucleoside diphosphates only to a minor extent (By similarity). In contrast to its human ortholog is able to hydrolyze ATP. In the epithelial cells of small intestine controls luminal ATP levels, therefore regulating Th17-cell development (PubMed:23241884). |
Cellular Location | Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:Q9NQZ7}; Multi-pass membrane protein |
Tissue Location | Widely expressed. Expressed at high level in brain, kidney, liver, testis and small intestin. Weakly expressed in lung, thymus and heart. |
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Provided below are standard protocols that you may find useful for product applications.
References
Shi J.-D.,et al.J. Biol. Chem. 276:17474-17478(2001).
Carninci P.,et al.Science 309:1559-1563(2005).
Okazaki N.,et al.Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
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