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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   JPH3 antibody - N-terminal region   

JPH3 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - JPH3 antibody - N-terminal region AI13044

    WB Suggested Anti-JPH3 Antibody Titration: 0.2-1 μg/ml
    Positive Control: HepG2 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8WXH2
Other Accession NM_020655, NP_065706
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 81kDa
Additional Information
Gene ID 57338
Alias Symbol CAGL237, FLJ44707, HDL2, JP-3, JP3, TNRC22
Other Names Junctophilin-3, JP-3, Junctophilin type 3, Trinucleotide repeat-containing gene 22 protein, JPH3, JP3, TNRC22
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-JPH3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsJPH3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name JPH3
Synonyms JP3, TNRC22
Function Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH3 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory.
Cellular Location Cell membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein Note=Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane (By similarity).
Tissue Location Specifically expressed in brain.
Research Areas
Citations (0)

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Nishi M.,et al.Biochem. Biophys. Res. Commun. 273:920-927(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Holmes S.E.,et al.Nat. Genet. 29:377-378(2001).
Stevanin G.,et al.Neurology 58:965-967(2002).
Walker R.H.,et al.Neurology 61:1002-1004(2003).

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$ 293.00
Cat# AI13044
(40 western blots)
Availability: 2-3 days
Bulk Size
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