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Aadacl1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q8BLF1 |
| Other Accession | NM_178772, NP_848887 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 46kDa |
| Gene ID | 320024 |
|---|---|
| Alias Symbol | Aadacl1, B230106I24Rik, CPO-BP, Nceh |
| Other Names | Neutral cholesterol ester hydrolase 1, NCEH, 3.1.1.-, Arylacetamide deacetylase-like 1, Chlorpyrifos oxon-binding protein, CPO-BP, Nceh1, Aadacl1, Kiaa1363 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Aadacl1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Aadacl1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Nceh1 |
|---|---|
| Synonyms | Aadacl1, Kiaa1363 |
| Function | Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2- acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (PubMed:18164358, PubMed:20625037). May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages (PubMed:18782767). Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (PubMed:15840715, PubMed:16978018, PubMed:18164358). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q6PIU2}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q6PIU2} Microsome |
| Tissue Location | Present in brain, heart, kidney, lung, spinal cord and testis but not liver (at protein level). Expressed in peritoneal macrophages and kidney. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Okazaki N.,et al.DNA Res. 11:205-218(2004).
Carninci P.,et al.Science 309:1559-1563(2005).
Leung D.,et al.Nat. Biotechnol. 21:687-691(2003).
Nomura D.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:6195-6200(2005).
Nomura D.K.,et al.Chem. Res. Toxicol. 19:1142-1150(2006).
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