|Other Accession||NM_178772, NP_848887|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||Aadacl1, B230106I24Rik, CPO-BP, Nceh|
|Other Names||Neutral cholesterol ester hydrolase 1, NCEH, 3.1.1.-, Arylacetamide deacetylase-like 1, Chlorpyrifos oxon-binding protein, CPO-BP, Nceh1, Aadacl1, Kiaa1363|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Aadacl1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Aadacl1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds.|
|Cellular Location||Membrane; Single-pass type II membrane protein. Microsome|
|Tissue Location||Present in brain, heart, kidney, lung, spinal cord and testis but not liver (at protein level). Expressed in peritoneal macrophages and kidney.|
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Provided below are standard protocols that you may find useful for product applications.
Okazaki N.,et al.DNA Res. 11:205-218(2004).
Carninci P.,et al.Science 309:1559-1563(2005).
Leung D.,et al.Nat. Biotechnol. 21:687-691(2003).
Nomura D.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 102:6195-6200(2005).
Nomura D.K.,et al.Chem. Res. Toxicol. 19:1142-1150(2006).
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