|Other Accession||NM_021267, NP_067090|
|Reactivity||Human, Mouse, Rat, Horse|
|Predicted||Human, Mouse, Rat, Horse|
|Alias Symbol||CerS1, LAG1, MGC90349, UOG1, LASS1|
|Other Names||Ceramide synthase 1, CerS1, LAG1 longevity assurance homolog 1, Longevity assurance gene 1 protein homolog 1, Protein UOG-1, CERS1, LAG1, LASS1, UOG1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LASS1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LASS1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||LAG1, LASS1, UOG1|
|Function||May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Lee S.-J.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:4250-4254(1991).
Jiang J.C.,et al.Genome Res. 8:1259-1272(1998).
Grimwood J.,et al.Nature 428:529-535(2004).
Bienvenut W.V.,et al.Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
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