|Other Accession||NM_024807, NP_079083|
|Reactivity||Human, Rat, Rabbit, Pig, Horse, Bovine, Dog|
|Predicted||Rabbit, Pig, Horse, Bovine, Dog|
|Alias Symbol||C6orf76, FLJ13693, MGC149715, MGC149716, TLT2, dJ238O23.1, TLT-2|
|Other Names||Trem-like transcript 2 protein, TLT-2, Triggering receptor expressed on myeloid cells-like protein 2, TREML2, C6orf76, TLT2|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TREML2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TREML2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Detected in cultured B-cells, T-cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation|
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Provided below are standard protocols that you may find useful for product applications.
Allcock R.J.N.,et al.Eur. J. Immunol. 33:567-577(2003).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Hashiguchi M.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10495-10500(2008).
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