|Other Accession||NM_031952, NP_114158|
|Reactivity||Human, Pig, Horse, Bovine, Dog|
|Alias Symbol||FLJ35906, NYD-SP16|
|Other Names||Spermatogenesis-associated protein 9, Testis development protein NYD-SP16, SPATA9|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-SPATA9 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||SPATA9 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in testicular development/spermatogenesis and may be an important factor in male infertility.|
|Cellular Location||Membrane; Single-pass membrane protein|
|Tissue Location||Highly expressed in testes and pancreas. Low levels found in the heart, lungs, and brain. Very low expression detected in the placenta. No expression seen in skeletal muscle, liver, kidney, thymus, small intestine, colons, spleen, leukocytes, prostate gland, and ovary. In the adult testes, expression was about 6.44-fold higher than in the embryo testes No expression in testes of patients with Sertoli-cell-only syndrome. In patients with arrest at spermatogonium and primary spermatocyte stages, no expression was detected. In patients with arrest at the spermatid stage, expression level was weak or absent. Variable expression was seen in patients with spermatogenic arrest.|
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Cheng L.J.,et al.Biol. Reprod. 68:190-198(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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