|Other Accession||NM_032738, NP_116127|
|Calculated MW||41 KDa|
|Alias Symbol||FCRL, FCRLM1, FCRLX, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FREB, MGC4595, RP11-474I16.5, FCRX, FCRL1|
|Other Names||Fc receptor-like A, Fc receptor homolog expressed in B-cells, Fc receptor-like and mucin-like protein 1, Fc receptor-like protein, Fc receptor-related protein X, FcRX, FCRLA, FCRL, FCRL1, FCRLM1, FCRX, FREB|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-FCRLA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||FCRLA antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FCRL, FCRL1, FCRLM1, FCRX, FREB|
|Function||May be implicated in B-cell differentiation and lymphomagenesis.|
|Cellular Location||Cytoplasm Note=Seems not to be secreted.|
|Tissue Location||Expressed specifically in primary and secondary lymphoid tissues like lymph node, spleen and tonsil Specifically expressed in B-cells with a high level in normal germinal center B-cells, centroblasts and in a subset of diffuse large B-cell lymphomas. Highly expressed in bone marrow B-cells and weakly in earlier B lineage cells. Expressed in pre-germinal and germinal center B-cells in secondary lymphoid tissues. Also expressed in melanoma and melanocytes|
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Provided below are standard protocols that you may find useful for product applications.
Mechetina L.V.,et al.Eur. J. Immunol. 32:87-96(2002).
Facchetti F.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:3776-3781(2002).
Davis R.S.,et al.Int. Immunol. 14:1075-1083(2002).
Inozume T.,et al.Int. J. Cancer 114:283-290(2005).
Guselnikov S.,et al.Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
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