|Other Accession||NM_033100, NP_149091|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||DKFZp434A132, KIAA1775, PRCAD, CORD15, PCDH21|
|Other Names||Cadherin-related family member 1, Photoreceptor cadherin, prCAD, Protocadherin-21, CDHR1, KIAA1775, PCDH21, PRCAD|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PCDH21 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PCDH21 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1775, PCDH21, PRCAD|
|Function||Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells (By similarity).|
|Cellular Location||Cell membrane; Single-pass membrane protein. Note=Localized at the junction between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin between postnatal days 2 and 9 at the base of the growing OS region (By similarity)|
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Provided below are standard protocols that you may find useful for product applications.
Deloukas P.,et al.Nature 429:375-381(2004).
Nakajima D.,et al.Brain Res. Mol. Brain Res. 94:85-95(2001).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Yang Z.,et al.J. Clin. Invest. 118:2908-2916(2008).
Ostergaard E.,et al.J. Med. Genet. 47:665-669(2010).
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