BRPF3 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9ULD4 |
Other Accession | NM_015695, NP_056510 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 136kDa |
Gene ID | 27154 |
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Other Names | Bromodomain and PHD finger-containing protein 3, BRPF3, KIAA1286 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-BRPF3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | BRPF3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BRPF3 {ECO:0000303|PubMed:26620551, ECO:0000312|HGNC:HGNC:14256} |
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Function | Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity (PubMed:16387653, PubMed:26620551, PubMed:26677226). Plays a role in DNA replication initiation by directing KAT7/HBO1 specificity towards histone H3 'Lys- 14' acetylation (H3K14ac), thereby facilitating the activation of replication origins (PubMed:26620551). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (PubMed:16387653). |
Cellular Location | Nucleus |
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Provided below are standard protocols that you may find useful for product applications.
References
Nagase T.,et al.DNA Res. 6:337-345(1999).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Doyon Y.,et al.Mol. Cell 21:51-64(2006).
Ullah M.,et al.Mol. Cell. Biol. 28:6828-6843(2008).
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