BRF2 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q9HAW0 |
Other Accession | NM_018310, NP_060780 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Chicken, Horse, Bovine, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 46kDa |
Gene ID | 55290 |
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Alias Symbol | BRFU, FLJ11052, TFIIIB50 |
Other Names | Transcription factor IIIB 50 kDa subunit, TFIIIB50, hTFIIIB50, B-related factor 2, BRF-2, hBRFU, BRF2, BRFU |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-BRF2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | BRF2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | BRF2 |
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Synonyms | BRFU {ECO:0000303|PubMed:11040218} |
Function | General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites (PubMed:11040218, PubMed:11121026, PubMed:11564744, PubMed:26638071). Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress (PubMed:26638071). Down-regulates expression of target genes in response to oxidative stress (PubMed:26638071). Overexpression protects cells against apoptosis in response to oxidative stress (PubMed:26638071). |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
References
Schramm L.,et al.Genes Dev. 14:2650-2663(2000).
Teichmann M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:14200-14205(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Yu Y.,et al.Genome Res. 11:1392-1403(2001).
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