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Plekhf2 antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q91WB4 |
| Other Accession | NM_175175, NP_780384 |
| Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig |
| Predicted | Mouse, Rat, Chicken, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 28kDa |
| Gene ID | 71801 |
|---|---|
| Alias Symbol | 1110070J07Rik, AA673237, ZFYVE18 |
| Other Names | Pleckstrin homology domain-containing family F member 2, PH domain-containing family F member 2, Plekhf2 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Plekhf2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Plekhf2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Plekhf2 |
|---|---|
| Function | May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport (By similarity). Enhances cellular sensitivity to TNF-induced apoptosis. |
| Cellular Location | Early endosome membrane {ECO:0000250|UniProtKB:Q9H8W4}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9H8W4}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9H8W4}. Note=Colocalizes with EEA1 and RAB5 at endosomal membrane fusion hot spots. May translocate to the endoplasmic reticulum in the early phase of apoptosis {ECO:0000250|UniProtKB:Q9H8W4} |
| Tissue Location | Expressed in brain, stomach and thymus, as well as in kidney, spleen, and skeletal muscle. Also expressed in peripheral blood mononuclear cells and dendritic cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Carninci P.,et al.Science 309:1559-1563(2005).
Li C.,et al.J. Mol. Med. 86:471-484(2008).
Trost M.,et al.Immunity 30:143-154(2009).
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