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>   home   >   Products   >   Primary Antibodies   >   PRDM6 antibody - N-terminal region   

PRDM6 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - PRDM6 antibody - N-terminal region AI13269

    WB Suggested Anti-PRDM6 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Jurkat cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NQX0
Other Accession XM_937753, XP_942846
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 67kDa
Additional Information
Gene ID 93166
Other Names Putative histone-lysine N-methyltransferase PRDM6,, PR domain zinc finger protein 6, PR domain-containing protein 6, PRDM6, PFM3
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PRDM6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPRDM6 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDM6
Synonyms PFM3
Function Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).
Cellular Location Nucleus.
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$ 293.00
Cat# AI13269
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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