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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   KLHDC5 antibody - middle region   

KLHDC5 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - KLHDC5 antibody - middle region AI13309

    WB Suggested Anti-KLHDC5 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Transfected 293T
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9P2K6
Other Accession NM_020782, NP_065833
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 57kDa
Additional Information
Gene ID 57542
Alias Symbol KIAA1340, MGC131714, Ctb9, KLHDC5
Other Names Kelch-like protein 42, Cullin-3-binding protein 9, Ctb9, Kelch domain-containing protein 5, KLHL42, KIAA1340, KLHDC5
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-KLHDC5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKLHDC5 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL42
Synonyms KIAA1340, KLHDC5
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. Involved in microtubule dynamics throughout mitosis.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, spindle Note=Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis
Research Areas
Citations (0)

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Scherer S.E.,et al.Nature 440:346-351(2006).
Nagase T.,et al.DNA Res. 7:65-73(2000).
Matsuoka S.,et al.Science 316:1160-1166(2007).
Cummings C.M.,et al.J. Biol. Chem. 284:11663-11675(2009).

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$ 293.00
Cat# AI13309
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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