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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   COPA antibody - N-terminal region   

COPA antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - COPA antibody - N-terminal region AI13341

    WB Suggested Anti-COPA Antibody Titration: 0.2-1 μg/ml
    Positive Control: Hela cell lysate
    COPA is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
  • WB - COPA antibody - N-terminal region AI13341

    Host: Rabbit
    Target Name: COPA
    Sample Tissue: Hela Whole Cell lysates
    Antibody Dilution: 3μg/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P53621
Other Accession NM_004371, NP_004362
Reactivity Human, Mouse, Rat, Rabbit, Pig, Goat, Horse, Yeast, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Pig, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 135kDa
Additional Information
Gene ID 1314
Alias Symbol FLJ26320, HEP-COP
Other Names Coatomer subunit alpha, Alpha-coat protein, Alpha-COP, HEP-COP, HEPCOP, Xenin, Xenopsin-related peptide, Proxenin, COPA
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-COPA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCOPA antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Cellular Location Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it
Tissue Location Uniformly expressed in a wide range of adult and fetal tissues. Xenin is found in gastric, duodenal and jejunal mucosa. Circulates in the blood. Seems to be confined to specific endocrine cells
Research Areas
Citations (0)

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Chow V.T.K.,et al.Gene 169:223-227(1996).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Feurle G.E.,et al.J. Biol. Chem. 267:22305-22309(1992).
Chow V.T.K.,et al.Ann. Hum. Genet. 61:369-373(1997).

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$ 293.00
Cat# AI13341
(40 western blots)
Availability: 2-3 days
Bulk Size
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