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AP1G1 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - AP1G1 antibody - C-terminal region AI13344

    WB Suggested Anti-AP1G1 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Human brain
    detail
  • WB - AP1G1 antibody - C-terminal region AI13344

    Host: Rabbit
    Target Name: AP1G1
    Sample Tissue: HepG2
    Antibody Dilution: 1.0μg/mlAP1G1 is supported by BioGPS gene expression data to be expressed in HepG2
    detail
  • WB - AP1G1 antibody - C-terminal region AI13344

    Host: Rabbit
    Target Name: AP1G1
    Sample Tissue: Jurkat
    Antibody Dilution: 1.0μg/mlAP1G1 is supported by BioGPS gene expression data to be expressed in Jurkat
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O43747
Other Accession NM_001128, NP_001119
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 91kDa
Additional Information
Gene ID 164
Alias Symbol ADTG, CLAPG1, MGC18255
Other Names AP-1 complex subunit gamma-1, Adaptor protein complex AP-1 subunit gamma-1, Adaptor-related protein complex 1 subunit gamma-1, Clathrin assembly protein complex 1 gamma-1 large chain, Gamma1-adaptin, Golgi adaptor HA1/AP1 adaptin subunit gamma-1, AP1G1, ADTG, CLAPG1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-AP1G1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsAP1G1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AP1G1
Synonyms ADTG, CLAPG1
Function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. In association with AFTPH/aftiphilin in the aftiphilin/p200/gamma-synergin complex, involved in the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (PubMed:15758025).
Cellular Location Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex (PubMed:12773381). Co-localizes with AFTPH/aftiphilin in the cytoplasm (PubMed:15758025).
Tissue Location Widely expressed.
Research Areas
Citations (0)
citation

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References

Peyrard M.,et al.Genomics 50:275-280(1998).
Takatsu H.,et al.J. Biol. Chem. 273:24693-24700(1998).
Martin J.,et al.Nature 432:988-994(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Deneka M.,et al.EMBO J. 22:2645-2657(2003).

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$ 389.00
Cat# AI13344
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