|Other Accession||NM_001267, NP_001258|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Chicken, Horse, Bovine, Dog|
|Other Names||Chondroadherin, Cartilage leucine-rich protein, CHAD, SLRR4A|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-CHAD antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CHAD antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation (By similarity).|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Present in chondrocytes at all ages.|
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Provided below are standard protocols that you may find useful for product applications.
Grover J.,et al.Genomics 45:379-385(1997).
Maansson B.,et al.J. Biol. Chem. 276:32883-32888(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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