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>   home   >   Products   >   Primary Antibodies   >   Dom3z antibody - N-terminal region   

Dom3z antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Dom3z antibody - N-terminal region AI13365

    WB Suggested Anti-Dom3z Antibody Titration: 1.0 μg/ml
    Positive Control: Rat Liver
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6MG77
Other Accession NM_212497, NP_997662
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 43kDa
Additional Information
Gene ID 361799
Alias Symbol MGC95256
Other Names Decapping and exoribonuclease protein, DXO, 3.1.13.-, 3.6.1.-, Dom-3 homolog Z, Dxo, Dom3z
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Dom3z antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsDom3z antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dxo
Synonyms Dom3z
Function Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping, pyrophosphohydrolase and 5'-3' exonuclease activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. The 5' end monophosphate RNA is then degraded by the 5'-3' exoribonuclease activity, enabling this enzyme to decap and degrade incompletely capped mRNAs. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity).
Cellular Location Nucleus.
Citations (0)

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Hurt P.,et al.Genome Res. 14:631-639(2004).

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$ 293.00
Cat# AI13365
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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