|Other Accession||NM_006347, NP_006338|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Chicken, Bovine, Dog|
|Alias Symbol||CYP-20, CYPH, MGC5016, SnuCyp-20, USA-CYP|
|Other Names||Peptidyl-prolyl cis-trans isomerase H, PPIase H, 188.8.131.52, Rotamase H, Small nuclear ribonucleoprotein particle-specific cyclophilin H, CypH, U-snRNP-associated cyclophilin SnuCyp-20, USA-CYP, PPIH, CYP20, CYPH|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-PPIH antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PPIH antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone.|
|Cellular Location||Nucleus speckle. Cytoplasm. Note=Colocalizes with spliceosomal snRNPs. A small proportion may also be cytoplasmic|
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Provided below are standard protocols that you may find useful for product applications.
Horowitz D.S.,et al.RNA 3:1374-1387(1997).
Teigelkamp S.,et al.RNA 4:127-141(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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