Hsph1 antibody - C-terminal region
Rabbit Polyclonal Antibody
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Application
| WB |
---|---|
Primary Accession | Q66HA8 |
Other Accession | NM_001011901, NP_001011901 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 94kDa |
Gene ID | 288444 |
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Alias Symbol | Hsp105 |
Other Names | Heat shock protein 105 kDa, Heat shock 110 kDa protein, Hsph1, Hsp105, Hsp110 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Hsph1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Hsph1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Hsph1 |
---|---|
Synonyms | Hsp105, Hsp110 |
Function | Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q92598}. |
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