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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Katna1 antibody - C-terminal region   

Katna1 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Katna1 antibody - C-terminal region AI13395

    WB Suggested Anti-Katna1 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Spleen
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9WV86
Other Accession NM_011835, NP_035965
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rabbit, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Additional Information
Other Names Katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}, Katanin p60 subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}, {ECO:0000255|HAMAP-Rule:MF_03023}, Lipotransin, p60 katanin {ECO:0000255|HAMAP-Rule:MF_03023}, Katna1
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Katna1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKatna1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Katna1
Function Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
Cellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03023}. Midbody {ECO:0000255|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255|HAMAP-Rule:MF_03023}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000255|HAMAP-Rule:MF_03023}. Note=Predominantly cytoplasmic. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase and telophase is localized at the midbody region. Also localized to the interphase centrosome and the mitotic spindle poles. Enhanced recruitment to the mitotic spindle poles requires microtubules and interaction with KATNB1. {ECO:0000255|HAMAP-Rule:MF_03023}
Research Areas
Citations (0)

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Syu L.-J.,et al.Mol. Cell 4:109-115(1999).
Karabay A.,et al.J. Neurosci. 24:5778-5788(2004).

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$ 293.00
Cat# AI13395
(40 western blots)
Availability: 2-3 days
Bulk Size
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