Mgll Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8R431 |
Other Accession | NM_138502, NP_612511 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 33kDa |
Gene ID | 29254 |
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Alias Symbol | MAGL |
Other Names | Monoglyceride lipase, MGL, 3.1.1.23, Monoacylglycerol lipase, MAGL, Mgll, Mgl2 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 &mu, l of distilled water. Final Anti-Mgll antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Mgll Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Mgll {ECO:0000312|RGD:71039} |
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Synonyms | Mgl2 |
Function | Converts monoacylglycerides to free fatty acids and glycerol (PubMed:12136125). Hydrolyzes the endocannabinoid 2- arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:12136125, PubMed:17649977). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (By similarity). |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35678}. Membrane {ECO:0000250|UniProtKB:O35678}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35678} |
Tissue Location | Ubiquitous. Highly expressed in adipose tissue, adrenal gland, ovary, heart, spleen, lung, skeletal muscle, kidney and testis. Highly expressed throughout the brain |
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Provided below are standard protocols that you may find useful for product applications.
References
Dinh T.P.,et al.Proc. Natl. Acad. Sci. U.S.A. 99:10819-10824(2002).
Karlsson M.,et al.J. Biol. Chem. 272:27218-27223(1997).
Lubec G.,et al.Submitted (DEC-2006) to UniProtKB.
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