|Other Accession||NM_024095, NP_077000|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Human, Mouse, Rat, Rabbit, Chicken, Bovine, Dog|
|Alias Symbol||FLJ21255, MGC5540, PP14212|
|Other Names||Ankyrin repeat and SOCS box protein 8, ASB-8, ASB8|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ASB8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ASB8 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.|
|Tissue Location||Highest level of expression in skeletal muscle. Also expressed in heart, brain, placenta, liver, kidney and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
Liu Y.,et al.Biochem. Biophys. Res. Commun. 300:972-979(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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