|Other Accession||NM_130810, NP_570722|
|Reactivity||Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Mouse, Rat, Pig, Chicken, Bovine, Dog|
|Alias Symbol||DYX1, DYXC1, EKN1, FLJ37882, MGC70618, RD|
|Other Names||Dyslexia susceptibility 1 candidate gene 1 protein, DYX1C1, EKN1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-DYX1C1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||DYX1C1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity. Axonemal dynein assembly factor required for ciliary motility.|
|Cellular Location||Nucleus. Cytoplasm.|
|Tissue Location||Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells|
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Provided below are standard protocols that you may find useful for product applications.
Taipale M.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:11553-11558(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:671-675(2006).
Wang Y.,et al.Neuroscience 143:515-522(2006).
Massinen S.,et al.Hum. Mol. Genet. 18:2802-2812(2009).
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