Abra antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q8BUZ1 |
Other Accession | NM_175456, NP_780665 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 41kDa |
Gene ID | 223513 |
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Alias Symbol | C130068O12Rik, STARS |
Other Names | Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling, STARS, Abra {ECO:0000312|MGI:MGI:2444891} |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Abra antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Abra antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Abra {ECO:0000312|MGI:MGI:2444891} |
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Function | Acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling. |
Cellular Location | Cytoplasm, myofibril, sarcomere. Cytoplasm, cytoskeleton. Note=Localized to the I-band of the sarcomere and to a lesser extent to the sarcomeric structure between Z-lines. |
Tissue Location | Expressed specifically in heart and skeletal muscle. |
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Provided below are standard protocols that you may find useful for product applications.
References
Arai A.,et al.J. Biol. Chem. 277:24453-24459(2002).
Carninci P.,et al.Science 309:1559-1563(2005).
Kuwahara K.,et al.Mol. Cell. Biol. 25:3173-3181(2005).
Barrientos T.,et al.J. Biol. Chem. 282:8393-8403(2007).
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