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Fbxo32 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Fbxo32 antibody - C-terminal region AI13470

    WB Suggested Anti-Fbxo32 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Heart
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9CPU7
Other Accession NM_026346, NP_080622
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Rat, Rabbit, Pig, Chicken, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 39kDa
Additional Information
Gene ID 67731
Alias Symbol 4833442G10Rik, AI430017, ATROGIN1, MAFbx, atrogin-1, Gm20361
Other Names F-box only protein 32, Atrogin-1, Muscle atrophy F-box protein, MAFbx, Fbxo32
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Fbxo32 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFbxo32 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Fbxo32
Function Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1 (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:Q969P5}. Nucleus {ECO:0000250|UniProtKB:Q969P5}. Note=Shuttles between cytoplasm and the nucleus. {ECO:0000250|UniProtKB:Q969P5}
Tissue Location Specifically expressed in cardiac and skeletal muscle
Research Areas
Citations (0)
citation

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References

Gomes M.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:14440-14445(2001).
Carninci P.,et al.Science 309:1559-1563(2005).

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$ 389.00
Cat# AI13470
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