|Other Accession||NM_152345, NP_689558|
|Reactivity||Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog|
|Predicted||Human, Rat, Pig, Bovine, Guinea Pig|
|Alias Symbol||FLJ20418, FLJ25555|
|Other Names||Ankyrin repeat domain-containing protein 13B, ANKRD13B|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ANKRD13B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ANKRD13B antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand- activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.|
|Cellular Location||Cell membrane. Late endosome. Early endosome. Note=Interaction with EGFR may enhance association with the cell membrane|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Tanno H.,et al.Mol. Biol. Cell 23:1343-1353(2012).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.