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ANKRD13B antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - ANKRD13B antibody - middle region AI13478

    WB Suggested Anti-ANKRD13B Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: Human heart
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q86YJ7
Other Accession NM_152345, NP_689558
Reactivity Human, Mouse, Rat, Pig, Bovine, Guinea Pig, Dog
Predicted Human, Rat, Pig, Bovine, Guinea Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 70kDa
Additional Information
Gene ID 124930
Alias Symbol FLJ20418, FLJ25555
Other Names Ankyrin repeat domain-containing protein 13B, ANKRD13B
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ANKRD13B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsANKRD13B antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANKRD13B
Function Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Cellular Location Cell membrane. Late endosome. Early endosome. Note=Interaction with EGFR may enhance association with the cell membrane
Research Areas
Citations (0)
citation

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References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Tanno H.,et al.Mol. Biol. Cell 23:1343-1353(2012).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).

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$ 389.00
Cat# AI13478
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