|Other Accession||NM_025582, NP_079858|
|Reactivity||Human, Mouse, Rat, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||Fam213b, PM/PGFS, AI836168, RP23-15L19.6, 2810405K02Rik|
|Other Names||Prostamide/prostaglandin F synthase, Prostamide/PG F synthase, Prostamide/PGF synthase, 22.214.171.124, Fam213b|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-2810405K02Rik antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||2810405K02Rik antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha).|
|Cellular Location||Cytoplasm, cytosol|
|Tissue Location||Mainly present in brain and spinal cord. In spinal cord, present in the superficial layer of the dorsal horn, in motor neurons of the ventral horn and in glia of the white matter of the spinal cord. In brain, expressed preferentially in the white matter bundles of the entire CNS of adult with less marked expression in neuronal cell bodies. Colocalizes with MBP in myelin sheaths but not in axons. Localizes to myelin sheaths (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Carninci P.,et al.Science 309:1559-1563(2005).
Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Moriuchi H.,et al.J. Biol. Chem. 283:792-801(2008).
Yoshikawa K.,et al.Brain Res. 1367:22-32(2011).
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