Asprv1 Antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q09PK2 |
Other Accession | NM_026414, AAI08358 |
Reactivity | Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 33kDa |
Gene ID | 67855 |
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Alias Symbol | 2300003P22Rik, AA986851, SASP, SASPase, Taps |
Other Names | Retroviral-like aspartic protease 1, 3.4.23.-, Skin-specific retroviral-like aspartic protease, SASPase, Skin aspartic protease, TPA-inducible aspartic proteinase-like protein, Asprv1 {ECO:0000312|MGI:MGI:1915105} |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Asprv1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Asprv1 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Asprv1 {ECO:0000312|MGI:MGI:1915105} |
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Function | Protease responsible for filaggrin processing, essential for the maintenance of a proper epidermis organization. |
Cellular Location | Membrane; Single-pass membrane protein |
Tissue Location | Highly expressed in stratified epithelia in skin, tongue, esophagus, forestomach and vagina. Also expressed in trachea, urinary bladder and thymus. Undetectable in simple epithelia. Within the epidermis, expressed exclusively in the granular layer (at protein level). Levels are elevated in benign skin tumors but are down- regulated in squamous cell carcinomas. |
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Provided below are standard protocols that you may find useful for product applications.
References
Rhiemeier V.,et al.Am. J. Pathol. 168:1354-1364(2006).
Matsui T.,et al.J. Biol. Chem. 281:27512-27525(2006).
Carninci P.,et al.Science 309:1559-1563(2005).
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