|Other Accession||NM_153015, NP_694560|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog|
|Predicted||Rat, Chicken, Bovine|
|Alias Symbol||FLJ30668, NET36|
|Other Names||Transmembrane protein 74, TMEM74|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-TMEM74 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TMEM74 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an essential role in autophagy. TMEM74-induced autophagy may involve PI3K signal transduction.|
|Cellular Location||Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in heart, lung, and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Yu C.,et al.Biochem. Biophys. Res. Commun. 369:622-629(2008).
He P.,et al.Autophagy 5:52-60(2009).
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