Eid2 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q6X7S9 |
Other Accession | NM_198425, NP_940817 |
Reactivity | Human, Mouse, Rat, Bovine, Guinea Pig, Dog |
Predicted | Human, Mouse, Rat, Bovine, Guinea Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 26kDa |
Gene ID | 386655 |
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Alias Symbol | Cri2, EID-2 |
Other Names | EP300-interacting inhibitor of differentiation 2, EID-2, CREBBP/EP300 inhibitor 2, EID-1-like inhibitor of differentiation 2, Eid2 {ECO:0000312|EMBL:AAH94513.1, ECO:0000312|MGI:MGI:2681174} |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Eid2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Eid2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Eid2 {ECO:0000312|EMBL:AAH94513.1, ECO:0000312|MGI:MGI:2681174} |
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Function | Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3- dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q8N6I1}. |
Tissue Location | Expressed in heart, brain, kidney and pancreas. Not detected in placenta. |
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Provided below are standard protocols that you may find useful for product applications.
References
Ji A.,et al.Gene 318:35-43(2003).
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