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PLEKHA7 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - PLEKHA7 antibody - middle region AI13539

    WB Suggested Anti-PLEKHA7 Antibody Titration: 0.2-1 μg/ml
    Positive Control: Hela cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q6IQ23
Other Accession NM_175058, NP_778228
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Rat, Rabbit, Chicken, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 127kDa
Additional Information
Gene ID 144100
Alias Symbol DKFZp686M22243
Other Names Pleckstrin homology domain-containing family A member 7, PH domain-containing family A member 7, PLEKHA7
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PLEKHA7 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPLEKHA7 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLEKHA7
Function Required for zonula adherens biogenesis and maintenance (PubMed:19041755). Acts via its interaction with CAMSAP3, which anchors microtubules at their minus-ends to zonula adherens, leading to the recruitment of KIFC3 kinesin to the junctional site (PubMed:19041755). Mediates docking of ADAM10 to zonula adherens through a PDZD11- dependent interaction with the ADAM10-binding protein TSPAN33 (PubMed:30463011).
Cellular Location Cell junction, adherens junction. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Localizes to zonula adherens, recruited via its interaction with CTNND1.
Research Areas
Citations (0)
citation

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References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Brill L.M.,et al.Anal. Chem. 76:2763-2772(2004).
Meng W.,et al.Cell 135:948-959(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).

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$ 389.00
Cat# AI13539
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