|Other Accession||NM_175882, NP_787078|
|Alias Symbol||SPPL2c, IMP5|
|Other Names||Signal peptide peptidase-like 2C, SPP-like 2C, SPPL2c, 3.4.23.-, Intramembrane protease 5, IMP-5, SPPL2C, IMP5|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-IMP5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||IMP5 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein; Lumenal side|
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Provided below are standard protocols that you may find useful for product applications.
Grigorenko A.P.,et al.Biochemistry (Mosc.) 67:826-834(2002).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Friedmann E.,et al.J. Biol. Chem. 279:50790-50798(2004).
Friedmann E.,et al.Nat. Cell Biol. 8:843-848(2006).
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