|Other Accession||NM_001130475, NP_001123947|
|Reactivity||Human, Rat, Pig, Horse|
|Predicted||Human, Rabbit, Horse|
|Other Names||THAP domain-containing protein 5, THAP5|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-THAP5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||THAP5 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) (PubMed:21110952). May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase (PubMed:19502560).|
|Tissue Location||Detected in heart (PubMed:19502560, PubMed:21195082). Detected in brain and muscle (at protein level) (PubMed:19502560). Highly expressed in the heart. Also found in brain and skeletal muscle (PubMed:19502560, PubMed:21195082)|
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Scherer S.W.,et al.Science 300:767-772(2003).
Balakrishnan M.P.,et al.Am. J. Physiol. 297:H643-H653(2009).
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