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FAM173B antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - FAM173B antibody - N-terminal region AI13562

    WB Suggested Anti-FAM173B Antibody Titration: 0.2-1 μg/ml
    Positive Control: Human Lung
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q6P4H8
Other Accession NM_199133, NP_954584
Reactivity Human
Predicted Human
Host Rabbit
Clonality Polyclonal
Calculated MW 26kDa
Additional Information
Gene ID 134145
Alias Symbol FLJ20667
Other Names Protein FAM173B, FAM173B
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-FAM173B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFAM173B antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATPSCKMT (HGNC:27029)
Function Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C, ATP5MC1 and ATP5MC2. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration (PubMed:29444090, PubMed:30530489). Promotes chronic pain (PubMed:29444090). Involved in persistent inflammatory and neuropathic pain: methyltransferase activity in the mitochondria of sensory neurons promotes chronic pain via a pathway that depends on the production of reactive oxygen species (ROS) and on the engagement of spinal cord microglia (PubMed:29444090).
Cellular Location Mitochondrion membrane; Single-pass membrane protein. Note=Localizes to mitochondrial cristae.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
citation

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References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).

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$ 389.00
Cat# AI13562
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