|Other Accession||NM_001464, NP_001455|
|Reactivity||Human, Rat, Pig|
|Predicted||Human, Rat, Pig|
|Alias Symbol||CRYN1, CRYN2, CT15, FTNB, PH-30b, PH30|
|Other Names||Disintegrin and metalloproteinase domain-containing protein 2, ADAM 2, Cancer/testis antigen 15, CT15, Fertilin subunit beta, PH-30, PH30, PH30-beta, ADAM2, FTNB|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ADAM2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ADAM2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed specifically in spermatogenic cells in the seminiferous cells. Not detected in fetal tissues|
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Provided below are standard protocols that you may find useful for product applications.
Vidaeus C.M.,et al.Mol. Reprod. Dev. 46:363-369(1997).
Gupta S.K.,et al.Biochem. Biophys. Res. Commun. 224:318-326(1996).
Burkin H.R.,et al.Genomics 40:190-192(1997).
Hall L.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
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