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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   FEM1B antibody - middle region   

FEM1B antibody - middle region

Rabbit Polyclonal Antibody

  • WB - FEM1B antibody - middle region AI13598

    WB Suggested Anti-FEM1B Antibody Titration: 0.2-1 μg/ml
    Positive Control: 721_B cell lysate
    FEM1B is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells
  • WB - FEM1B antibody - middle region AI13598
    Lanes: 1: 30ug HEK293T cell lysate
    , 2: 30ug 3FLAG-hFEM1B transfected HEK293T cell lysate

    Primary Antibody Dilution: 1:1000
    Secondary Antibody: Anti-rabbit HRP
    Secondary Antibody Dilution: 1:8000
    Gene Name: FEM1B
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UK73
Other Accession NM_015322, NP_056137
Reactivity Human, Mouse, Rat, Rabbit, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rat, Rabbit, Pig, Chicken, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 69kDa
Additional Information
Gene ID 10116
Alias Symbol DKFZp451E0710, FIAA, F1A-ALPHA
Other Names Protein fem-1 homolog B, FEM1b, FEM1-beta, Fem-1-like death receptor-binding protein alpha, Fem-1-like in apoptotic pathway protein alpha, F1A-alpha, FEM1B, F1AA, KIAA0396
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-FEM1B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsFEM1B antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FEM1B
Synonyms F1AA, KIAA0396
Function Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
Cellular Location Cytoplasm. Nucleus. Note=In the nucleus, the protein level increased slightly after camptothecin (CPT) treatment. Associated with chromatin
Tissue Location Widely expressed. Highly expressed in testis. Weakly expressed in other tissues.
Research Areas
Citations (0)

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Chan S.-L.,et al.J. Biol. Chem. 274:32461-32468(1999).
Ventura-Holman T.,et al.Biochem. Biophys. Res. Commun. 267:317-320(2000).
Ishikawa K.,et al.DNA Res. 4:307-313(1997).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 293.00
Cat# AI13598
(40 western blots)
Availability: 2-3 days
Bulk Size
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